Agomelatine CAS: 138112-76-2
Basic Information: Product Name: Agomelatine CAS Number: 138112-76-2 Chinese Alias: N-(2-(7-Methoxynaphth-1-yl)ethyl)acetamide Molecular Formula: C15H17NO2 Molecular Weight: 243.30 English Name: Agomelatine EINECS: 629-727-7 Density: 1.109 g/cm³ English Alias: Thymanax; N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide; S 20098; Valdoxan; Acetamide, N-(2-(7-methoxy-1-naphthalenyl)ethyl)- Flash Point: 243.4°C Melting Point: 107-109°C Boiling Point: 478.8°C at 760 mmHg
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Product Description
Product Name: N-[2-(7-Methoxynaphthalen-1-yl)ethyl]acetamide
English Name: Agomelatine
Alternative English Names: N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide; N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide
CAS No.: 138112-76-2
Molecular Formula: C15H17NO2
Molecular Weight: 243.3082
Purity: 99.0%
Appearance: White to off-white crystalline powder
Packaging: 1 kg/bag; 25 kg/drum
Storage Conditions: Store in a sealed, dry, room temperature environment away from direct sunlight.
Note: All products of our company are for export only, intended for laboratory and research use in legal and non-patented regions. Personal or animal use is strictly prohibited, and those who misuse it illegally are fully responsible for any consequences.
1. Product Introduction: Agomelatine was launched in Europe in 2009. It works by targeting melatonin and serotonin receptors in the brain. As a melatonin receptor agonist, this mechanism helps restore natural circadian rhythms. Additionally, agomelatine acts as an antagonist to the 5-HT2C receptor. Furthermore, agomelatine may offer other benefits, making it an exciting area for future research.
2. Features:
(1) High Purity: Agomelatine can achieve high purity through refined production processes.
(2) Safety: High safety with minimal adverse reactions.
(3) Stability: Agomelatine has good stability, maintaining its activity and efficacy under different environmental and storage conditions.
3. Applications: Agomelatine is a dietary supplement additive that functions by regulating the melatonin MT1 receptor (reducing cortical alert signals) and MT2 receptor (circadian rhythm sleep patterns) and serotonin levels. Taken at night, it mimics the natural release rhythm of melatonin, activating the melatonin receptors MT1 and MT2, and antagonizing the 5-HT2C receptor. By antagonizing the 5-HT2C receptor on the postsynaptic membrane, it increases the release of DA and NE in the prefrontal cortex. When the MT agonistic effect coexists with the 5-HT2C receptor antagonistic effect, a unique synergistic effect is produced, promoting the release of more DA and NE in the PFC brain region.

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